Bowelcancer Frame

Colonic Physiology Ursula M. Szmulowicz and Tracy L. Hull The human colon is a dynamic call reed organ, touch on in a vast array of functions, including the submerging of water and electrolytes, the lay away of unabsorbed nutrients, and the transport of luminal contents as feces. While not an organ essential for life, the colon soundless plays a major numerical function in maintaining the overall wellness of the human body. Understanding these physiologic principles is integral to the happy treatment both aesculapian and surgical of colonic disease. Embryology The embryology of the colon informs its anatomy. In the third and fourth calendar hebdomads of gestation, the inexperienced intestine arises from the cephalocaudal and lateral crease of the dorsal surface of the endoderm-lined yolk sackful, forming a straight tube situated posteriorly in the embryo.13 Although the mucosa originates from the endoderm of the yolk sac, the muscular wall, connective tissue, and serosa perk up a mesodermal etiology. 4 By the fourth week of gestation, the intestine tube develops into leash distinct regions: the foregut, midgut, and hindgut.4 The midgut begins immediately distal to the confluence of the ballpark bile furrow and the duodenum, extending to include the proximal two-thirds of the cross(prenominal) colon.

At the midgut, the archaic intestine maintains its connection to the yolk sac via the vitelline duct; failure of the vitelline duct to obliterate ultimately results in a Meckels diverticulum or a vitelline cyst or fistula.2,5 The hindgut reaches from the distal third of the transversal colon to the anal groove proximal to the dentate line. The midgut receives its vascular supply from the superior(p) mesenteric artery and the hindgut from the inferior mesenteric artery.6 The colon gains its ultimate pip by means of a series of rotations of the embryonic gut. During the 5th week of gestation, the midgut, particularly the future ileum, rapidly enlarges beyond the capacity of the abdominal cavity,...If you unavoidableness to get a plentiful essay, order it on our website: Ordercustompaper.com

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